Article
Pharmacogenomic analysis of mechanisms mediating ethanol regulation of dopamine beta-hydroxylase.
The Journal of biological chemistry - 3 Oct 2003
Hassan Sajida, Duong Bao, Kim Kwang-Soo, Miles Michael F
Abstract excerpt
We previously showed that ethanol regulates dopamine beta-hydroxylase (DBH) mRNA and protein levels in human neuroblastoma cells (Thibault, C., Lai, C., Wilke, N., Duong, B., Olive, M. F., Rahman, S., Dong, H., Hodge, C. W., Lockhart, D. J., and Miles, M. F. (2000) Mol. Pharmacol. 58, 1593-1600). DBH catalyzes norepinephrine synthesis, and several studies have suggested a role for norepinephrine in...
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