Article
Human genetics of plasma dopamine beta-hydroxylase activity: applications to research in psychiatry and neurology.
Psychopharmacology - 1 Aug 2004
Cubells J F, Zabetian C P
Abstract excerpt
RATIONALE: Norepinephrine (NE) is a key neurotransmitter in the central and peripheral nervous systems. Dopamine beta-hydroxylase (DbetaH) catalyzes the synthesis of NE from dopamine (DA) and occurs in the plasma as a stable heritable trait. Studies of this trait have been useful in psychiatric and neurological research. OBJECTIVE: To selectively and critically review the literature on plasma DbetaH, and on...
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