Article
C-terminal peptides of p53 molecules enhance radiation-induced apoptosis in human mutant p53 cancer cells.
Apoptosis : an international journal on programmed cell death - 1 Sept 2004
Ohnishi K, Inaba H, Yasumoto J, Yuki K, Takahashi A, Ohnishi T
Abstract excerpt
We propose here a novel p53-targeting radio-cancer therapy using p53 C-terminal peptides for patients having mutated p53. Hoechst 33342 staining showed that X-ray irradiation alone efficiently induced apoptotic bodies in wild-type p53 (wt p53) human head and neck cancer cells transfected with a n...
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