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Article

Insights into the requirement of phosphatidylcholine synthesis for liver function in mice.

Journal of lipid research - 1 Oct 2003

Noga Anna A, Vance Dennis E

Abstract excerpt

Phosphatidylcholine (PC) is made in the liver by the CDP-choline pathway and via phosphatidylethanolamine N-methyltransferase (PEMT), which catalyzes the conversion of phosphatidylethanolamine to PC. Unexpectedly, hepatic apolipoprotein B-100 secretion is inhibited in male, but not female, Pemt-/- mice (Noga, A. A., Y. Zhao, and D. E. Vance. 2002. J. Biol. Chem. 277: 42358-42365; Noga, A. A., and D. E. Vance....

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Source

Identifiers

PMID: 12837848
DOI: 10.1194/jlr.M300226-JLR200

Genes

PEMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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