Article
Complementation of the metabolic defect in CTP:phosphoethanolamine cytidylyltransferase (Pcyt2)-deficient primary hepatocytes.
Metabolism: clinical and experimental - 1 Dec 2010
Fullerton Morgan D, Bakovic Marica
Abstract excerpt
The CTP:phosphoethanolamine cytidylyltransferase gene (Pcyt2) regulates the synthesis of CDP-ethanolamine, which is combined with diacylglycerol (DAG) to form the membrane phospholipid phosphatidylethanolamine (PE) via the de novo Kennedy pathway. [¹⁴C]Ethanolamine and [³H]glycerol radiolabeling...
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