Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasites.

Molecular biology and evolution - 1 Sept 2003

Nair Shalini, Williams Jeff T, Brockman Alan, Paiphun Lucy, Mayxay Mayfong, Newton Paul N, Guthmann Jean-Paul, Smithuis Frank M, Hien Tran Tinh, White Nicholas J, Nosten François, Anderson Tim J C

Abstract excerpt

Malaria parasites (Plasmodium falciparum) provide an excellent system in which to study the genomic effects of strong selection in a recombining eukaryote because the rapid spread of resistance to multiple drugs during the last the past 50 years has been well documented, the full genome sequence and a microsatellite map are now available, and haplotype data can be easily generated. We examined microsatellite...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimalarials
Share to Asia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance

Share to Malaria

Share to Malaria, Falciparum

Share to Pyrimethamine

Share to Selection, Genetic

Share to Tetrahydrofolate Dehydrogenase

Source

Identifiers

PMID: 12832643
DOI: 10.1093/molbev/msg162

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasites.PMID 12832643Read ↗

Hitchhiking and selective sweeps of Plasmodium falciparum sulfadoxine and pyrimethamine resistance alleles in a population from central Africa.Semantic proximity Read ↗

Reduced variation around drug-resistant dhfr alleles in African Plasmodium falciparum.Semantic proximity Read ↗

A major genome region underlying artemisinin resistance in malaria.Semantic proximity Read ↗

Antifolate antimalarial resistance in southeast Africa: a population-based analysis.Semantic proximity Read ↗

Intercontinental spread of pyrimethamine-resistant malaria.Semantic proximity Read ↗

A genome-wide map of diversity in Plasmodium falciparum.Semantic proximity Read ↗

Genomic Footprints of Selective Sweeps from Metabolic Resistance to Pyrethroids in African Malaria Vectors Are Driven by Scale up of Insecticide-Based Vector Control.Semantic proximity Read ↗

Selection strength and hitchhiking around two anti-malarial resistance genes.Semantic proximity Read ↗

Genome sequencing of Plasmodium malariae identifies continental segregation and mutations associated with reduced pyrimethamine susceptibility.Semantic proximity Read ↗

Distinctive origin and spread route of pyrimethamine-resistant Plasmodium falciparum in southern China.Semantic proximity Read ↗

Origins and spread of pfdhfr mutant alleles in Plasmodium falciparum.Semantic proximity Read ↗

Limited geographical origin and global spread of sulfadoxine-resistant dhps alleles in Plasmodium falciparum populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.