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Article

Hitchhiking and selective sweeps of Plasmodium falciparum sulfadoxine and pyrimethamine resistance alleles in a population from central Africa.

Antimicrobial agents and chemotherapy - 1 Nov 2008

McCollum Andrea M, Basco Leonardo K, Tahar Rachida, Udhayakumar Venkatachalam, Escalante Ananias A

Abstract excerpt

Sulfadoxine-pyrimethamine (SP) resistance in Plasmodium falciparum is encoded by a number of mutations in the dihydrofolate reductase (dhfr) and dihydropteroate synthetase (dhps) genes. Here, we have characterized point mutations in dhfr and dhps and microsatellite loci around dhfr on chromosome...

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Source

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Identifiers

PMID: 18765692
DOI: 10.1128/AAC.00623-08
PMCID: PMC2573158

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18765692-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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