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Article

Generation and functional characterization of a clonal murine periportal Kupffer cell line from H-2Kb -tsA58 mice.

Journal of leukocyte biology - 1 Jul 2003

Dory Daniel, Echchannaoui Hakim, Letiembre Maryse, Ferracin Fabrizia, Pieters Jean, Adachi Yoshiyuki, Akashi Sachiko, Zimmerli Werner, Landmann Regine

Abstract excerpt

Murine Kupffer cells (KCs) are heterogeneous and survive only for a short time in vitro. Here, a clonal, murine KC line was generated from transgenic mice, expressing the thermolabile mutant tsA58 of the Simian virus 40 large T antigen under the control of the H-2K(b) promoter. Thirty-three degrees Celsius and 37 degrees C but not 39 degrees C have been permissive for growth of the clone; it required conditioned...

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PMID: 12832442
DOI: 10.1189/jlb.0302133

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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