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Article

Kupffer cells express a unique combination of phenotypic and functional characteristics compared with splenic and peritoneal macrophages.

Journal of leukocyte biology - 1 Oct 2012

Movita Dowty, Kreefft Kim, Biesta Paula, van Oudenaren Adri, Leenen Pieter J M, Janssen Harry L A, Boonstra Andre

Abstract excerpt

The immunostimulatory role of Kupffer cells in various inflammatory liver diseases is still not fully understood. In this study, phenotypic and functional aspects of Kupffer cells from healthy C57BL/6 mice were analyzed and compared with those of splenic and peritoneal macrophages to generate a b...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22685319
DOI: 10.1189/jlb.1111566

Genes

TLR4
TLR7
TLR9
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22685319-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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