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Article

WEB-THERMODYN: Sequence analysis software for profiling DNA helical stability.

Nucleic acids research - 1 Jul 2003

Huang Yanlin, Kowalski David

Abstract excerpt

WEB-THERMODYN analyzes DNA sequences and computes the DNA helical stability, i.e. the free energy required to unwind and separate the strands of the double helix. A helical stability profile across a selected DNA region or the entire sequence is generated by sliding-window analysis. WEB-THERMODYN can predict sites of low helical stability present at regulatory regions for transcription and replication and can be...

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Identifiers

PMID: 12824427
DOI: 10.1093/nar/gkg562
PMCID: PMC168969

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