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Article

Fibroblast growth factor-2 but not Mel-CAM and/or beta3 integrin promotes progression of melanocytes to melanoma.

Experimental dermatology - 1 Jun 2003

Meier Friedegund, Caroli Ulrich, Satyamoorthy Kapaettu, Schittek Birgit, Bauer Jürgen, Berking Carola, Möller Helga, Maczey Evelyn, Rassner Gernot, Herlyn Meenhard, Garbe Claus

Abstract excerpt

A variety of melanoma-associated antigens have been identified that mediate adhesion, growth, proteolysis, and modulation of immune response. However, the mechanisms by which human normal melanocytes become malignant are not clearly understood. Among the most consistent observations is the up-regulation of fibroblast growth factor-2 (FGF-2) and of the adhesion molecules beta3 integrin and Mel-CAM during melanoma...

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Identifiers

PMID: 12823444
DOI: 10.1034/j.1600-0625.2003.120310.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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