Article
Phenotypes and interactions of human melanocytes and keratinocytes in an epidermal reconstruction model.
Laboratory investigation; a journal of technical methods and pathology - 1 Mar 1990
Valyi-Nagy I T, Murphy G F, Mancianti M L, Whitaker D, Herlyn M
Abstract excerpt
The morphologic and antigenic phenotype of normal human melanocytes and keratinocytes was investigated in monolayer and 3-dimensional cultures in an effort to develop an epidermal model that resembles the normal human epidermis. When cultured for several passages in optimal growth medium, pure cultures of either cell type could be established as demonstrated by light and electron microscopy and with monoclonal...
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