Article
Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs.
The Journal of biological chemistry - 5 Sept 2003
Olsen Shaun K, Garbi Meirav, Zampieri Niccolo, Eliseenkova Anna V, Ornitz David M, Goldfarb Mitchell, Mohammadi Moosa
Abstract excerpt
Fibroblast growth factors (FGFs) interact with heparan sulfate glycosaminoglycans and the extracellular domains of FGF cell surface receptors (FGFRs) to trigger receptor activation and biological responses. FGF homologous factors (FHF1-FHF4; also known as FGF11-FGF14) are related to FGFs by substantial sequence homology, yet their only documented interactions are with an intracellular kinase scaffold protein,...
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