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Article

Effects of coexpression with Homer isoforms on the function of metabotropic glutamate receptor 1alpha.

Molecular and cellular neurosciences - 1 Jun 2003

Abe Hideki, Misaka Takumi, Tateyama Michihiro, Kubo Yoshihiro

Abstract excerpt

We previously showed that the metabotropic glutamate receptor 1alpha (mGluR1alpha) has a sensitivity to extracellular polyvalent cations such as Ca(2+) and Gd(3+) as well as glutamate. Here we show that mGluR1alpha-mediated responses to these ligands are modulated by the scaffold protein Homer. When HEK293 cells were transiently cotransfected with Homer 1c and mGluR1alpha, the maximum rate of rise and amplitude...

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Identifiers

PMID: 12812750
DOI: 10.1016/s1044-7431(03)00052-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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