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Article

Strategies for selecting subsets of single-nucleotide polymorphisms to genotype in association studies.

BMC genetics - 30 Dec 2005

Butler Joe M, Bishop D Timothy, Barrett Jennifer H

Abstract excerpt

In genetic association studies, linkage disequilibrium (LD) within a region can be exploited to select a subset of single-nucleotide polymorphisms (SNPs) to genotype with minimal loss of information. A novel entropy-based method for selecting SNPs is proposed and compared to an existing method based on the coefficient of determination (R2) using simulated data from Genetic Analysis Workshop 14. The effect of the...

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Identifiers

PMID: 16451686
DOI: 10.1186/1471-2156-6-S1-S72
PMCID: PMC1866709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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