Article
Renal and blood pressure phenotype in 18-mo-old bradykinin B2R(-/-)CRD mice.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Oct 2003
Harrison-Bernard Lisa M, Dipp Susana, El-Dahr Samir S
Abstract excerpt
Aberrant gene-environment interactions are implicated in the pathogenesis of congenital renal dysgenesis (CRD), a leading cause of renal failure in infants and children. We have recently developed an animal model of CRD that is caused by gestational salt stress (5% NaCl diet; HS) of bradykinin B2R null mice [B2R(-/-)CRD; El-Dahr SS, Harrison-Bernard LM, Dipp S, Yosipiv IV, and Meleg-Smith S. Physiol Genomics 3:...
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