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Article

Renin-angiotensin system in kidney development: renal tubular dysgenesis.

Kidney international - 1 Mar 2010

Gubler Marie Claire, Antignac Corinne

Abstract excerpt

Autosomal recessive renal tubular dysgenesis (RTD) is a severe disorder of renal tubular development characterized by early onset and persistent fetal anuria leading to oligohydramnios and the Potter sequence. At birth, blood pressure is dramatically low and perinatal death occurs in most cases. Skull ossification defects are frequently associated with RTD. The disease is genetically heterogeneous and linked to...

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Identifiers

PMID: 19924102
DOI: 10.1038/ki.2009.423

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REN

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