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Article

Role of the angiotensin receptor in the development of the mammalian kidney and urinary tract.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology - 1 Jan 2001

Miyazaki Y, Ichikawa I

Abstract excerpt

Recent gene targeting and pharmacological studies have shown that the renin-angiotensin system is essential for the development of the mammalian kidney and urinary tract system. We have generated mutant mice carrying a targeted null mutation of the angiotensin type 1 receptor (AT1) or type 2 receptor (AT2) gene. Analyses of these two mutant mice revealed that both mutants have a distinct phenotype in the kidney...

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PMID: 11137441
DOI: 10.1016/s1095-6433(00)00299-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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