Article
High-salt diet reveals the hypertensive and renal effects of reduced nephron endowment.
American journal of physiology. Renal physiology - 1 Jun 2010
Ruta Leah-Anne M, Dickinson Hayley, Thomas Merlin C, Denton Kate M, Anderson Warwick P, Kett Michelle M
Abstract excerpt
The extent to which a reduced nephron endowment contributes to hypertension and renal disease is confounded in models created by intrauterine insults that also demonstrate other phenotypes. Furthermore, recent data suggest that a reduced nephron endowment provides the "first hit" and simply incre...
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