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Article

Role of the angiotensin type 2 receptor gene in congenital anomalies of the kidney and urinary tract, CAKUT, of mice and men.

Molecular cell - 1 Jan 1999

Nishimura H, Yerkes E, Hohenfellner K, Miyazaki Y, Ma J, Hunley T E, Yoshida H, Ichiki T, Threadgill D, Phillips J A, Hogan B M, Fogo A, Brock J W, Inagami T, Ichikawa I

Abstract excerpt

Angiotensin type 2 receptor gene null mutant mice display congenital anomalies of the kidney and urinary tract (CAKUT). Various features of mouse CAKUT impressively mimic human CAKUT. Studies of the human type 2 receptor (AGTR2) gene in two independent cohorts found that a significant association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10024874
DOI: 10.1016/s1097-2765(00)80169-0

Genes

AGTR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10024874-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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