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Article

Drosophila chk2 plays an important role in a mitotic checkpoint in syncytial embryos.

FEBS letters - 19 Jun 2003

Xu Jinhua, Du Wei

Abstract excerpt

Drosophila chk2 (Dmchk2, also called Dmnk) plays a crucial role in the DNA damage response pathway mediating cell cycle arrest and apoptosis [Xu et al., FEBS Lett. 508 (2001) 394-398; Peters et al., Proc. Natl. Acad. Sci. USA 99 (2002) 11305-11310]. In this study, the role of Dmchk2 in early embryogenesis was investigated. In the absence of Dmchk2 function, abnormal nuclei accumulate in the cortex of the...

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Identifiers

PMID: 12804777
DOI: 10.1016/s0014-5793(03)00536-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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