Article
Transmission of HIV-1 drug resistance mutations within partner-pairs: A cross-sectional study of a primary HIV infection cohort.
PLoS medicine - 1 Mar 2018
Stekler Joanne D, Milne Ross, Payant Rachel, Beck Ingrid, Herbeck Joshua, Maust Brandon, Deng Wenjie, Tapia Kenneth, Holte Sarah, Maenza Janine, Stevens Claire E, Mullins James I, Collier Ann C, Frenkel Lisa M
Abstract excerpt
BACKGROUND: Transmission of human immunodeficiency virus type 1 (HIV-1) drug resistance mutations, particularly that of minority drug-resistant variants, remains poorly understood. Population-based studies suggest that drug-resistant HIV-1 is less transmissible than drug-susceptible viruses. We compared HIV-1 drug-resistant genotypes among partner-pairs in order to assess the likelihood of transmission of drug...
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