Article
Persistence of multidrug-resistant HIV-1 without antiretroviral treatment 2 years after sexual transmission.
Antiviral therapy - 1 Jun 2004
Delaugerre Constance, Morand-Joubert Laurence, Chaix Marie-Laure, Picard Odile, Marcelin Anne-Genevieve, Schneider Veronique, Krivine Anne, Compagnucci Alexandra, Katlama Christine, Girard Pierre-Marie, Calvez Vincent
Abstract excerpt
OBJECTIVES: To understand the virological mechanisms of 2-year persistence of multidrug-resistant virus without selective antiretroviral pressure in HIV-1-infected patients. PATIENTS AND METHODS: Two patients were contaminated recently by their HIV-1-infected partners, who had received, before the transmission, all available antiretroviral drugs and who exhibited a severe therapeutic failure. The resistance...
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