Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolutionary pathways of transmitted drug-resistant HIV-1

18 Apr 2011

Abstract excerpt

Several large studies in Europe and the USA revealed that approximately 10% of all newly diagnosed patients harbour HIV-1 variants with at least one major resistance-associated mutation. In this review we discuss the underlying mechanisms that drive the evolution of drug-resistant viruses after transmission to the new host. In a comprehensive literature search 12 papers describing the evolution of 58 cases of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV/AIDS Research and Interventions
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21502281
DOI: 10.1093/jac/dkr157

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolutionary pathways of transmitted drug-resistant HIV-1PMID 21502281Read ↗

Evolution and viral characteristics of a long-term circulating resistant HIV-1 strain in a cluster of treatment-naive patients.Semantic proximity Read ↗

Insights about minority HIV-1 strains in transmitted drug resistance mutation dynamics and disease progression.Semantic proximity Read ↗

Antiviral drug resistance as an adaptive processSemantic proximity Read ↗

Genetic Consequences of Antiviral Therapy on HIV-1.Semantic proximity Read ↗

Stability of transmitted drug-resistant HIV-1 species.Semantic proximity Read ↗

Evolution of drug-resistant viral populations during interruption of antiretroviral therapy.Semantic proximity Read ↗

[Molecular mechanisms for the emergence of drug-resistant HIV-1].Semantic proximity Read ↗

HIV‐1 evolution in relation to molecular epidemiology and antiretroviral resistanceSemantic proximity Read ↗

Novel drug resistance mutations in HIV: recognition and clinical relevance.Semantic proximity Read ↗

Prevalence and persistence of transmitted drug resistance mutations in the German HIV-1 Seroconverter Study CohortSemantic proximity Read ↗

Evolution of transmitted HIV-1 with drug-resistance mutations in the absence of therapy: effects on CD4+ T-cell count and HIV-1 RNA load.Semantic proximity Read ↗

Evolution of resistance to drugs in HIV-1-infected patients failing antiretroviral therapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.