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Article

Transmission of antiretroviral-drug-resistant HIV-1 variants.

Lancet (London, England) - 28 Aug 1999

Yerly S, Kaiser L, Race E, Bru J P, Clavel F, Perrin L

Abstract excerpt

BACKGROUND: Resistance of HIV-1 to antiretroviral drugs is the main cause of antiretroviral-treatment failure. We assessed the transmission of drug-resistant variants among individuals with primary HIV-1 infection. METHODS: Population-based sequencing of the viral reverse-transcriptase and protease genes derived from plasma viral RNA was done in 82 consecutive individuals with documented primary HIV-1 infection...

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Identifiers

PMID: 10475184
DOI: 10.1016/S0140-6736(98)12262-6

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