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Article

TNF-alpha protects embryos exposed to developmental toxicants.

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Mar 2003

Torchinsky Arkady, Shepshelovich Jeanne, Orenstein Hasida, Zaslavsky Zeev, Savion Shoshana, Carp Howard, Fain Amos, Toder Vladimir

Abstract excerpt

BACKGROUND: Tumor necrosis factor alpha (TNF-alpha) has been implicated in mediating post-implantation embryo loss or the embryonic maldevelopment induced by development toxicants or maternal metabolic imbalances. In order to clarify the role of TNF-alpha further, a comparative study was performed in TNF-alpha, knockout and TNF-alpha, positive mice, exposed to a reference teratogen, cyclophosphamide (CP)....

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Identifiers

PMID: 12797522
DOI: 10.1034/j.1600-0897.2003.01174.x

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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