Cyclophosphamide, methotrexate, and cytarabine embropathy: Is apoptosis the common pathway?

Abstract excerpt

BACKGROUND: Cyclophosphamide (CP) is an alkylating agent primarily used for the treatment of autoimmune disease and cancer. The purpose of this article is two-fold: first, to indicate that CP is a recognized human teratogen based on the features seen in a child prenatally exposed to this agent, as well as features seen in the previously reported cases; second, to suggest a common pathway to explain the similarity...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Acute Lymphoblastic Leukemia research
• Share to Chemotherapy-induced organ toxicity mitigation
• Share to Pregnancy and Medication Impact