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Article

Radiation-induced tissue abnormalities in fetal brain are related to apoptosis immediately after irradiation.

International journal of radiation biology - 1 May 2000

Kubota Y, Takahashi S, Sun X Z, Sato H, Aizawa S, Yoshida K

Abstract excerpt

PURPOSE: To investigate the relation between the incidence of radiation-induced tissue abnormalities in fetal brain and the extent of p53-dependent apoptosis. MATERIALS AND METHODS: Pregnant mice with wild-type p53(+/+), heterozygous p53(+/-) and homozygous mutant p53(-/-) fetuses received whole-body X-irradiation on day 13 of gestation. The extent of apoptosis 6 hr after irradiation and the incidence of tissue...

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Identifiers

PMID: 10866287
DOI: 10.1080/095530000138312

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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