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Article

Selection of genetic markers for association analyses, using linkage disequilibrium and haplotypes.

American journal of human genetics - 1 Jul 2003

Meng Zhaoling, Zaykin Dmitri V, Xu Chun-Fang, Wagner Michael, Ehm Margaret G

Abstract excerpt

The genotyping of closely spaced single-nucleotide polymorphism (SNP) markers frequently yields highly correlated data, owing to extensive linkage disequilibrium (LD) between markers. The extent of LD varies widely across the genome and drives the number of frequent haplotypes observed in small regions. Several studies have illustrated the possibility that LD or haplotype data could be used to select a subset of...

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PMID: 12796855
DOI: 10.1086/376561
PMCID: PMC1180574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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