Article
Haplotype-based linkage disequilibrium mapping via direct data mining.
Bioinformatics (Oxford, England) - 15 Dec 2005
Li Jing, Jiang Tao
Abstract excerpt
MOTIVATION: With the availability of large-scale, high-density single-nucleotide polymorphism markers and information on haplotype structures and frequencies, a great challenge is how to take advantage of haplotype information in the association mapping of complex diseases in case-control studies. RESULTS: We present a novel approach for association mapping based on directly mining haplotypes (i.e. phased...
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