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Article

Linkage disequilibrium-based quality control for large-scale genetic studies.

PLoS genetics - 1 Aug 2008

Scheet Paul, Stephens Matthew

Abstract excerpt

Quality control (QC) is a critical step in large-scale studies of genetic variation. While, on average, high-throughput single nucleotide polymorphism (SNP) genotyping assays are now very accurate, the errors that remain tend to cluster into a small percentage of "problem" SNPs, which exhibit unusually high error rates. Because most large-scale studies of genetic variation are searching for phenomena that are...

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Identifiers

PMID: 18670630
DOI: 10.1371/journal.pgen.1000147
PMCID: PMC2475504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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