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Article

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes.

Science (New York, N.Y.) - 6 Jun 2003

Zou Lee, Elledge Stephen J

Abstract excerpt

The function of the ATR (ataxia-telangiectasia mutated- and Rad3-related)-ATRIP (ATR-interacting protein) protein kinase complex is crucial for the cellular response to replication stress and DNA damage. Here, we show that replication protein A (RPA), a protein complex that associates with single...

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Share to Ataxia Telangiectasia Mutated Proteins
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Source

Identifiers

PMID: 12791985
DOI: 10.1126/science.1083430

Genes

ATRIP
ATR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12791985-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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