Article
Isolation of Listeria monocytogenes mutants with high-level in vitro expression of host cytosol-induced gene products.
Molecular microbiology - 1 Jun 2003
Shetron-Rama Lynne M, Mueller Kimberly, Bravo Juan M, Bouwer H G Archie, Way Sing Sing, Freitag Nancy E
Abstract excerpt
The facultative intracellular bacterial pathogen Listeria monocytogenes dramatically increases the expression of several key virulence factors upon entry into the host cell cytosol. actA, the protein product of which is required for cell-to-cell spread of the bacterium, is expressed at low to undetectable levels in vitro and increases in expression more than 200-fold after L. monocytogenes escape from the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.