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Article

Glutathione activates virulence gene expression of an intracellular pathogen.

Nature - 8 Jan 2015

Reniere Michelle L, Whiteley Aaron T, Hamilton Keri L, John Sonya M, Lauer Peter, Brennan Richard G, Portnoy Daniel A

Abstract excerpt

Intracellular pathogens are responsible for much of the world-wide morbidity and mortality due to infectious diseases. To colonize their hosts successfully, pathogens must sense their environment and regulate virulence gene expression appropriately. Accordingly, on entry into mammalian cells, the facultative intracellular bacterial pathogen Listeria monocytogenes remodels its transcriptional program by activating...

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Identifiers

PMID: 25567281
DOI: 10.1038/nature14029
PMCID: PMC4305340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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