Article
Response of short tandem repeat systems to temperature and sizing methods.
Forensic science international - 5 May 2003
Hartzell Brittany, Graham Kylie, McCord Bruce
Abstract excerpt
In capillary gel electrophoresis (CE), changing run conditions such as temperature can result in minor variations in the size determination of an allele. These effects are caused by secondary structure differences that can occur between the amplified sample and the internal standard. The type of method chosen to generate the sizing curve in STR analysis can influence the relationship between estimated allele size...
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