Article
Sensitivity, reproducibility, and accuracy in short tandem repeat genotyping using capillary array electrophoresis.
Genome research - 1 Sept 1996
Mansfield E S, Vainer M, Enad S, Barker D L, Harris D, Rappaport E, Fortina P
Abstract excerpt
The Human Genome Initiative has increased significantly the rate at which disease-causing genes are being mapped and sequenced. New cost-effective methods to locate the genes and to characterize disease-causing mutations require robust, reproducible, and accurate protocols for measuring DNA fragm...
Topics
- Capillary Action
- DNA
- Dinucleotide Repeats
- Electrophoresis
- Genetic Markers
- Genotype
- Human Genome Project
- Humans
- Oligodeoxyribonucleotides
- Polymerase Chain Reaction
- Proteins
- Reference Standards
- Repetitive Sequences, Nucleic Acid
- Reproducibility of Results
- Sensitivity and Specificity