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Article

Involvement of an SCFSlmb complex in timely elimination of E2F upon initiation of DNA replication in Drosophila.

BMC genetics - 4 Jun 2003

Hériché Jean-Karim, Ang Dan, Bier Ethan, O'Farrell Patrick H

Abstract excerpt

BACKGROUND: Cul1 is a core component of the evolutionarily conserved SCF-type ubiquitin ligases that target specific proteins for destruction. SCF action contributes to cell cycle progression but few of the key targets of its action have been identified. RESULTS: We found that expression of the mouse Cul1 (mCul1) in the larval wing disc has a dominant negative effect. It reduces, but does not eliminate, the...

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Source

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Identifiers

PMID: 12787468
DOI: 10.1186/1471-2156-4-9
PMCID: PMC161817

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Involvement of an SCFSlmb complex in timely elimination of E2F upon initiation of DNA replication in Drosophila.PMID 12787468Read ↗

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