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Article

The SCF ubiquitin ligase protein slimb regulates centrosome duplication in Drosophila.

Current biology : CB - 21 Sept 2000

Wojcik E J, Glover D M, Hays T S

Abstract excerpt

The duplication of the centrosome is a key event in the cell-division cycle. Although defects in centrosome duplication are thought to contribute to genomic instability [1-3] and are a hallmark of certain transformed cells and human cancer [4-6], the mechanism responsible for centrosome duplication is not understood. Recent experiments have established that centrosome duplication requires the activity of...

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PMID: 10996795
DOI: 10.1016/s0960-9822(00)00703-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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