Article
HPC2/ELAC2 gene variants associated with incident prostate cancer.
Journal of human genetics - 1 Jan 2003
Adler David, Kanji Nimira, Trpkov Kiril, Fick Gordon, Hughes Rhiannon M
Abstract excerpt
The HPC2/ELAC2 gene on chromosome 17p11 was identified as a candidate gene for hereditary prostate cancer (HPC) susceptibility. Two HPC2 gene missense variants, Ser217Leu (Leu217) and Ala541Thr (Thr541) have been associated with incident prostate cancer cases in some studies, but not in others. We tested for possible associations between the two HPC2 gene variants and prostate cancer risk in incident prostate...
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