Article
HPC2/ELAC2 polymorphisms and prostate cancer risk: analysis by age of onset of disease.
British journal of cancer - 7 Oct 2002
Meitz J C, Edwards S M, Easton D F, Murkin A, Ardern-Jones A, Jackson R A, Williams S, Dearnaley D P, Stratton M R, Houlston R S, Eeles R A
Abstract excerpt
The candidate prostate cancer susceptibility gene HPC2/ELAC2 has two common coding polymorphisms: (Ser-->Leu 217) and (Ala-->Thr 541). The Thr541 variant in the HPC2/ELAC2 gene has previously been reported to be at an increased frequency in prostate cancer cases. To evaluate this hypothesis we ge...
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