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Article

HPC2/ELAC2 polymorphisms and prostate cancer risk: analysis by age of onset of disease.

British journal of cancer - 7 Oct 2002

Meitz J C, Edwards S M, Easton D F, Murkin A, Ardern-Jones A, Jackson R A, Williams S, Dearnaley D P, Stratton M R, Houlston R S, Eeles R A

Abstract excerpt

The candidate prostate cancer susceptibility gene HPC2/ELAC2 has two common coding polymorphisms: (Ser-->Leu 217) and (Ala-->Thr 541). The Thr541 variant in the HPC2/ELAC2 gene has previously been reported to be at an increased frequency in prostate cancer cases. To evaluate this hypothesis we genotyped 432 prostate cancer patients (including 262 patients diagnosed <or=55 years) and 469 UK, population based...

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Source

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Identifiers

PMID: 12373607
DOI: 10.1038/sj.bjc.6600564
PMCID: PMC2376179

Genes

ELAC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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