Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Marrow stem cells shift gene expression and engraftment phenotype with cell cycle transit.

The Journal of experimental medicine - 2 Jun 2003

Lambert Jean-Francois, Liu Meng, Colvin Gerald A, Dooner Mark, McAuliffe Christina I, Becker Pamela S, Forget Bernard G, Weissman Sherman M, Quesenberry Peter J

Abstract excerpt

We studied the genetic and engraftment phenotype of highly purified murine hematopoietic stem cells (lineage negative, rhodamine-low, Hoechst-low) through cytokine-stimulated cell cycle. Cells were cultured in interleukin (IL)-3, IL-6, IL-11, and steel factor for 0 to 48 h and tested for engraftment capacity in a lethally irradiated murine competitive transplant model. Engraftment showed major fluctuations with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematopoietic Stem Cell Transplantation

Share to Hematopoietic Stem Cells

Share to Interleukin-3

Share to Interleukin-6

Share to Mice, Inbred BALB C

Share to Stem Cell Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 12782718
DOI: 10.1084/jem.20030031
PMCID: PMC2193900

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Marrow stem cells shift gene expression and engraftment phenotype with cell cycle transit.PMID 12782718Read ↗

The marrow cell continuum: stochastic determinism.Semantic proximity Read ↗

The stem cell continuum: cell cycle, injury, and phenotype lability.Semantic proximity Read ↗

Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fatesSemantic proximity Read ↗

A new stem cell biology: the continuum and microvesicles.Semantic proximity Read ↗

Divisional history and hematopoietic stem cell function during homeostasis.Semantic proximity Read ↗

A culture platform to study quiescent hematopoietic stem cells following genome editingSemantic proximity Read ↗

Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycleSemantic proximity Read ↗

Human Haematopoietic Stem Cells released into circulation following mobilization express multiple G0-associated quiescence markersSemantic proximity Read ↗

Molecular signatures of proliferation and quiescence in hematopoietic stem cells.Semantic proximity Read ↗

Adaptation to <i>ex vivo</i> culture drives human haematopoietic stem cell loss of repopulation capacity in a cell cycle independent mannerSemantic proximity Read ↗

Phenotype of the engrafting stem cell in mice.Semantic proximity Read ↗

Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potentialSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.