Article
A new stem cell biology: the continuum and microvesicles.
Transactions of the American Clinical and Climatological Association - 1 Jan 2012
Quesenberry Peter J, Dooner Mark S, Goldberg Laura R, Aliotta Jason M, Pereira Mandy, Amaral Ashley, Del Tatto Michael M, Hixson Douglas C, Ramratnam Bharat
Abstract excerpt
The hierarchical models of stem cell biology have been based on work first demonstrating pluripotental spleen-colony-forming units, then showing progenitors with many differentiation fates assayed in in vitro culture; there followed the definition and separation of "stem cells" using monoclonal antibodies to surface epitopes and fluorescent-activated cell characterization and sorting (FACS). These studies led to...
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