Article
Heparan sulfate 6-o-sulfotransferase is essential for muscle development in zebrafish.
The Journal of biological chemistry - 15 Aug 2003
Bink Robert J, Habuchi Hiroko, Lele Zsolt, Dolk Edward, Joore Jos, Rauch Gerd-Jörg, Geisler Robert, Wilson Stephen W, den Hertog Jeroen, Kimata Koji, Zivkovic Danica
Abstract excerpt
Heparan sulfate proteoglycans function in development and disease. They consist of a core protein with attached heparan sulfate chains that are altered by a series of carbohydrate-modifying enzymes and sulfotransferases. Here, we report on the identification and characterization of a gene encoding zebrafish heparan sulfate 6-O-sulfotransferase (hs6st) that shows high homology to other heparan sulfate...
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