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Article

Heparan 2-O-sulfotransferase, hst-2, is essential for normal cell migration in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 1 Feb 2005

Kinnunen Tarja, Huang Zebo, Townsend Joanne, Gatdula Michelle M, Brown Jillian R, Esko Jeffrey D, Turnbull Jeremy E

Abstract excerpt

The importance of heparan sulfate proteoglycans has been highlighted by a number of human genetic disorders associated with mutations in genes encoding for heparan sulfate proteoglycan protein cores or biosynthetic enzymes required for heparan sulfate (HS) assembly. To study the functional role of HS in Caenorhabditis elegans development cosmid sequence C34F6.4 was identified as the C. elegans ortholog of...

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Identifiers

PMID: 15671174
DOI: 10.1073/pnas.0401591102
PMCID: PMC547812

Genes

FGF2

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