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Article

Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity.

The EMBO journal - 2 Jun 2003

Nakayama Jun-Ichi, Xiao Guoping, Noma Ken-Ichi, Malikzay Asra, Bjerling Pernilla, Ekwall Karl, Kobayashi Ryuji, Grewal Shiv I S

Abstract excerpt

The post-translational modifications of histones are key to the modulation of chromatin structure. Distinct patterns of modifications established by histone-modifying enzymes control diverse chromosomal processes. Here, we report the purification and molecular characterization of the fission yeast Clr6 histone deacetyl ase involved in higher order chromatin assembly. We show that a chromodomain protein Alp13,...

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Identifiers

PMID: 12773392
DOI: 10.1093/emboj/cdg248
PMCID: PMC156745

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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