Article
Histone deacetylase homologs regulate epigenetic inheritance of transcriptional silencing and chromosome segregation in fission yeast.
Genetics - 1 Oct 1998
Grewal S I, Bonaduce M J, Klar A J
Abstract excerpt
Position-effect control at the silent mat2-mat3 interval and at centromeres and telomeres in fission yeast is suggested to be mediated through the assembly of heterochromatin-like structures. Therefore, trans-acting genes that affect silencing may encode either chromatin proteins, factors that mo...
Topics
- Amino Acid Sequence
- Cell Cycle Proteins
- Centromere
- Chromosome Segregation
- Chromosomes, Fungal
- Cloning, Molecular
- Enzyme Inhibitors
- Genes, Fungal
- Histone Deacetylase Inhibitors
- Hydroxamic Acids
- Meiosis
- Molecular Sequence Data
- Mutation
- Open Reading Frames
- RNA, Fungal
- RNA, Messenger
- Recombination, Genetic
- Schizosaccharomyces