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Article

Histone deacetylase homologs regulate epigenetic inheritance of transcriptional silencing and chromosome segregation in fission yeast.

Genetics - 1 Oct 1998

Grewal S I, Bonaduce M J, Klar A J

Abstract excerpt

Position-effect control at the silent mat2-mat3 interval and at centromeres and telomeres in fission yeast is suggested to be mediated through the assembly of heterochromatin-like structures. Therefore, trans-acting genes that affect silencing may encode either chromatin proteins, factors that modify them, or factors that affect chromatin assembly. Here, we report the identification of an essential gene, clr6...

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Identifiers

PMID: 9755190
DOI: 10.1093/genetics/150.2.563
PMCID: PMC1460350

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Histone deacetylase homologs regulate epigenetic inheritance of transcriptional silencing and chromosome segregation in fission yeast.PMID 9755190Read ↗

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Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation.Semantic proximity Read ↗

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