Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling

30 Oct 2013

Abstract excerpt

The chromatin regulatory factor SIRT6 plays pivotal roles in metabolism, tumor suppression, and aging biology. Despite the fundamental roles of SIRT6 in physiology and disease, only a handful of molecular and functional interactions of SIRT6 have been reported. Here, we characterize the SIRT6 interactome and identify 80+ novel SIRT6-interacting proteins. The discovery of these SIRT6-associations considerably...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Endoplasmic Reticulum Stress and Disease
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24169447
DOI: 10.1038/srep03085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signalingPMID 24169447Read ↗

SIRT6Semantic proximity Read ↗

The Histone Deacetylase SIRT6: At the Crossroads Between Epigenetics, Metabolism and DiseaseSemantic proximity Read ↗

SIRT6, a Mammalian Deacylase with Multitasking AbilitiesSemantic proximity Read ↗

Advances in Cellular Characterization of the Sirtuin Isoform, SIRT7Semantic proximity Read ↗

Chromatin and beyond: the multitasking roles for SIRT6Semantic proximity Read ↗

Functional dissection of SIRT6: Identification of domains that regulate histone deacetylase activity and chromatin localizationSemantic proximity Read ↗

Sirt6 Deacetylase: A Potential Key Regulator in the Prevention of Obesity, Diabetes and Neurodegenerative DiseaseSemantic proximity Read ↗

The conserved role of sirtuins in chromatin regulationSemantic proximity Read ↗

Functional Proteomics Establishes the Interaction of SIRT7 with Chromatin Remodeling Complexes and Expands Its Role in Regulation of RNA Polymerase I TranscriptionSemantic proximity Read ↗

Functional Proteomics Establishes the Interaction of SIRT7 with Chromatin Remodeling Complexes and Expands Its Role in Regulation of RNA Polymerase I TranscriptionSemantic proximity Read ↗

Sub-cellular localization, expression and functions of Sirt6 during the cell cycle in HeLa cellsSemantic proximity Read ↗

Emerging roles of SIRT6 in human diseases and its modulatorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.