Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of anatomical distribution of mast cells on their defense function against bacterial infections: demonstration using partially mast cell-deficient tg/tg mice.

The Journal of experimental medicine - 2 Jun 2003

Jippo Tomoko, Morii Eiichi, Ito Akihiko, Kitamura Yukihiko

Abstract excerpt

Mast cells were depleted in the peritoneal cavity of WBB6F1-tg/tg mice that did not express a transcription factor, MITF. When acute bacterial peritonitis was induced in WBB6F1-+/+, WBB6F1-W/Wv, and WBB6F1-tg/tg mice, the proportion of surviving WBB6F1-+/+ mice was significantly higher than that of surviving WBB6F1-W/Wv or WBB6F1-tg/tg mice. The poor survival of WBB6F1-W/Wv and WBB6F1-tg/tg mice was attributed to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Infections
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mast Cells

Share to Mice, Mutant Strains

Share to Mice, Transgenic

Share to Microphthalmia-Associated Transcription Factor

Share to Peritoneal Cavity

Share to Peritonitis

Source

Open in PubMed Open full text

Identifiers

PMID: 12771178
DOI: 10.1084/jem.20022157
PMCID: PMC2193916

Genes

MITF
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of anatomical distribution of mast cells on their defense function against bacterial infections: demonstration using partially mast cell-deficient tg/tg mice.PMID 12771178Read ↗

Distinct roles for the SgIGSF adhesion molecule and c-kit receptor tyrosine kinase in the interaction between mast cells and the mesentery.Semantic proximity Read ↗

Number of mast cells in the peritoneal cavity of mice: influence of microphthalmia transcription factor through transcription of newly found mast cell adhesion molecule, spermatogenic immunoglobulin superfamily.Semantic proximity Read ↗

Dermal mast cells play a central role in the incidence of scratching behavior in mice induced by multiple application of the hapten, 2,4,6-trinitrochlorobenzene.Semantic proximity Read ↗

Roles of MITF for development of mast cells in mice: effects on both precursors and tissue environments.Semantic proximity Read ↗

Mast cells promote homeostasis by limiting endothelin-1-induced toxicity.Semantic proximity Read ↗

Strain-dependent inhibitory effect of mutant mi-MITF on cytotoxic activities of cultured mast cells and natural killer cells of mice.Semantic proximity Read ↗

Alteration of protease expression phenotype of mouse peritoneal mast cells by changing the microenvironment as demonstrated by in situ hybridization histochemistry.Semantic proximity Read ↗

Mast cell-dependent control of Giardia lamblia infections in mice.Semantic proximity Read ↗

Neutrophils exacerbate tuberculosis infection in genetically susceptible mice.Semantic proximity Read ↗

Expression of mast-cell-specific proteases in tissues of mice studied by in situ hybridization.Semantic proximity Read ↗

Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice.Semantic proximity Read ↗

Role of mast cells in ion transport abnormalities associated with intestinal anaphylaxis. Correction of the diminished secretory response in genetically mast cell-deficient W/Wv mice by bone marrow transplantation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.