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Article

Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice.

The Journal of allergy and clinical immunology - 1 Oct 2013

Reber Laurent L, Marichal Thomas, Mukai Kaori, Kita Yoshihiro, Tokuoka Suzumi M, Roers Axel, Hartmann Karin, Karasuyama Hajime, Nadeau Kari C, Tsai Mindy, Galli Stephen J

Abstract excerpt

BACKGROUND: Studies with c-kit mutant mast cell (MC)-deficient mice and antibody-mediated depletion of basophils suggest that both MCs and basophils can contribute to peanut-induced anaphylaxis (PIA). However, interpretation of data obtained by using such approaches is complicated because c-kit mutant mice have several phenotypic abnormalities in addition to MC deficiency and because basophil-depleting antibodies...

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Identifiers

PMID: 23915716
DOI: 10.1016/j.jaci.2013.06.008
PMCID: PMC3794715

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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