Article
Microsatellite instability and p53 expression in gallbladder carcinomas.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Jun 2003
Sessa Fausto, Furlan Daniela, Genasetti Anna, Billo Paola, Feltri Maddalena, Capella Carlo
Abstract excerpt
We studied the MSI (microsatellite instability) status and p53 expression in a series of 71 gallbladder cancers (GCs) of different histologic type. All neoplasms were examined combining a microsatellite analysis at mononucleotide locus BAT-26 and an immunohistochemical study for hMSH2, hMLH1, and p53 proteins and markers of gastric and intestinal differentiation. All the 71 GCs were MSS (microsatellite stable)....
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